Arizona Cardinals to play San Francisco 49ers in Mexico City in 2022 NFL season

Jeremy Cluff
Arizona Republic
In this Oct. 2, 2005, file photo, Azteca Stadium in Mexico City, Mexico is shown prior to the start of a regular season NFL game between the Arizona Cardinals and San Francisco 49ers.

The Arizona Cardinals will be returning to Mexico City in 2022.

The NFL announced Wednesday that the team will play a regular season game at Estadio Azteca in Mexico City as part of the 2022 NFL season.

The Cardinals will face the San Francisco 49ers in Week 11 on Monday, Nov. 21.

The game will kick off at 6:15 p.m. Arizona time.

With NFL teams now playing 17 games each season, the Cardinals will now play eight 2022 regular season games at State Farm Stadium in Glendale, eight on the road, and the game in Mexico City, a neutral-site game.

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In 2005, the Cardinals earned a 31-14 win over the 49ers at Estadio Azteca in front of a then-record crowd of 103,467 in the team's first game in Mexico City. It was the NFL's first regular season game held outside the United States. 

The Cardinals' game in Mexico City in 2022 will be the NFL's fifth at Estadio Azteca.

In 2019, the Kansas City Chiefs earned a 24-17 victory over the Los Angeles Chargers at Estadio Azteca on Monday Night Football, two-and-a-half months before winning Super Bowl LIV.

Estadio Azteca also hosted the Patriots-Raiders in 2017 and Texans-Raiders in 2016.

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The Cardinals and 49ers will join the Raiders as the only teams to have played multiple regular season games at Estadio Azteca.

The Cardinals also played in the first NFL game outside of North America when they played the Chargers in a preseason game in Tokyo, Japan on Aug. 16, 1976.

The game in Mexico City will air on ESPN with Monday Night Football’s new announcer booth of Joe Buck (play-by-play) and Troy Aikman (analyst) calling the action.

Tickets for the game in Mexico City will be available in August. To receive information on tickets and hospitality, visit www.azcardinals.com/intlgame.  

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.

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