Kansas City Chiefs vs. San Francisco 49ers picks, predictions: Who wins NFL Week 7 game?

The Kansas City Chiefs and San Francisco 49ers play on Sunday in a game on the NFL Week 7 schedule.

Which team will get the victory?

Check out these NFL Week 7 picks and predictions for the game, which can be seen at 1:25 p.m. MST on Fox.

The Chiefs are a 3.5-point favorite in the game.

NFL Week 7 picks, predictions:

• Saints vs. Cardinals | Browns vs. Ravens | Bucs vs. Panthers
• Falcons vs. Bengals | Lions vs. Cowboys | Giants vs. Jaguars
• Colts vs. Titans | Packers vs. Commanders | Jets vs. Broncos
• Texans vs. Raiders | Seahawks vs. Chargers | Chiefs vs. 49ers
• Steelers vs. Dolphins | Bears vs. Patriots | Republic's picks

The Arizona Republic: Chiefs 27, 49ers 24

Jeremy Cluff writes: "Both of these teams are coming off tough losses, but the 49ers looked bad against the Falcons."

Bookies.com: Take the Chiefs on the moneyline vs. 49ers

Bill Speros writes: "The 49ers were flocked over by the Falcons 28-14 in Atlanta. This game is a rematch of Super Bowl 54, won by the Chiefs 31-20. Kansas City trailed 20-10 in that game entering the 4th quarter. Jimmy G. self-immolated and Mahomes led a 3-TD assault in the final 6:13. The Chiefs won their Super Bowl 55 rematch at Tampa Bay earlier this season. Look for them to run their Super Bowl Rematch streak to 2-0 this season. A loss here leaves the 49ers below .500 but no more than one game back in their division."

NFL Week 7 odds:

• Saints vs. Cardinals | Browns vs. Ravens | Bucs vs. Panthers
• Falcons vs. Bengals | Lions vs. Cowboys | Giants vs. Jaguars
• Colts vs. Titans | Packers vs. Commanders | Jets vs. Broncos
• Texans vs. Raiders | Seahawks vs. Chargers | Chiefs vs. 49ers
• Steelers vs. Dolphins | Bears vs. Patriots | Odds, betting info.

ESPN: Chiefs have a 70.8% chance to win the Week 7 game

The site's Football Power Index gives the 49ers a 28.9% chance to get the victory.

Draft Kings: Go with the Chiefs to cover vs. 49ers

David Fucillo writes: "This line is going to be an interesting one to watch. 49ers head coach Kyle Shanahan said Nick Bosa and Trent Williams could both come back this week. The injury reports this week could move this line a fair amount depending on what we see from those two. The 49ers will be in a better position with those two back, but this is also arguably a less important game than the following week on the road against the Rams. I suspect we see Bosa and/or Williams get another week of rest. Wins are wins, but a win over a division-mate in a tight race like the NFC West will be the key to necessary tiebreakers. All of which suggests to me that the 49ers take one on the chin in this one."

How to watch:NFL Week 7 schedule, television information

Sports Betting Dime: 49ers 21.6, Chiefs 19

The site's formula predicts the 49ers will win the Week 7 NFL game.

ATS.IO: Bet the 49ers with the points vs. Chiefs

Jay Sanin writes: " San Francisco has the best defense in the NFL coming into this contest against the Chiefs. The Niners are number one in the league in yards allowed per game this season. They are also number two in the league in scoring defense. They will continue to dominate opponents on defense in this matchup with the high-flying Chiefs, en route to a huge victory."

NFL power rankings:New York Giants, New York Jets make statements with big wins

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on Twitter @Jeremy_Cluff.

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